Abstract:Objective To evaluate the efficacy and safety of Traditional Chinese Medicine in the treatment of allergic cough(AC), and to provide reference for clinical treatment and related research. Methods Randomized controlled clinical trials of treating allergic cough with traditional Chinese medicine alone as treatment group and conventional western medicine as control group were retrieved from relevant literature databases by computer. Meta-analysis using RevMan 5.3 software. Results A total of 14 studies were included, with a total of 1,223 patients, 610 cases in the treatment group and 613 cases in the control group. Meta-analysis results showed that, the total effective rate of the treatment group was significantly higher than that of the control group[RR=1.22, 95%CI(1.16, 1.29), P<0.000 01], the total effective rate of subgroup analysis by age is also that of the treatment group is better than that of the control group, the cough symptom score after treatment was lower than that of the control group[Z=2.01, P<0.000 01, MD=-2.23, 95%CI(-4.41,-0.06)], the eosinophils count after treatment was less than that in the control group[Z=1.66, P<0.000 01, SMD=-3.37, 95%CI(-7.34, 0.61)]. Conclusion The clinical efficacy of traditional Chinese medicine in the treatment of allergic cough is better than that of conventional western medicine, and the safety is high.However, due to the low quality and quantity of the included literature, this study has some limitations.Therefore,a higher quality RCT is still needed for further confirmation.