煨脓长肉中医外治法促进伤口愈合随机对照试验的系统评价*
作者:
作者单位:

(1. 陕西中医药大学,陕西 咸阳 712000;2. 陕西中医药大学附属医院,陕西 咸阳 712000)

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R269

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收稿日期: 2019 - 12- 10
* 基金项目: 中国民族医药学会科研项目(2019KYXM-Z1119-80);咸阳市科学技术研究计划项目(2018k02-97)
第一作者简介: 程嘉骏(1995-),男, 在读硕士研究生,研究方向:中医肛肠疾病的临床及实验。
△通信作者: 冯文哲,E-mail: szfygck@163.com


A Randomized Controlled Trial of External Treatment of Traditional Chinese Medicine to Promote Wound Healing under the Theory of Simmering Pus and Growing Meat: A Systematic Evaluation
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(1. Shaanxi University of Traditional Chinese Medicine, Xianyang 712000, China 2. Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Xianyang 712000, China)

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    摘要:

    目的系统评价国内煨脓长肉理论下中医外治法促进伤口愈合的临床疗效。方法 通过计算机检索中国知网(CNKI)、维普(VIP)及万方数据库(WANFANG DATA),收集煨脓长肉外治法促进伤口愈合的随机对照试验(RCT),按照纳入标准和排除标准对文献进行筛选和数据提取。运用RevMan 5.3软件对提取数据进行Meta分析,比较中医与西医常规促进伤口愈合外治法的临床有效率,以及有关生化指标的变化。结果 Meta分析结果显示,煨脓长肉理论下中医外治法促进伤口愈合的效果优于常规西医外治法,如凡士林油纱条、康复新液、0.1%利凡诺纱条等;但本文遗憾点在于纳入的研究大部分并未报道复发率、生活质量及不良反应,无法对这些指标进一步分析。结论 本研究显示,与常规促进伤口愈合的西医外治法相比,煨脓长肉中医外治法在促进伤口愈合方面有更好的疗效;但由于纳入文献数量较少,质量较低,所以日后需要设计严谨、合理的大样本随机对照试验进行进一步的研究。

    Abstract:

    Objective To evaluate systematically the clinical efficacy of Chinese external treatment in promoting wound healing under the theory of simmer pus and long meat in China. Methods Through the computer retrieval of CNKI, VIP and Wanfang database, the RCT of promoting wound healing by external treatment of traditional Chinese medicine under the theory of simmer pus and long meat was collected, and the literature was screened and data extracted according to the inclusion criteria and exclusion criteria. Using Rev man 5.3 software to Meta analyze the extracted data, and compare the clinical efficiency of external treatment of traditional Chinese medicine and Western medicine, which generally promotes wound healing, as well as the changes of various biochemical indicators. Results The results of Meta-analysis showed that under the theory of simmer pus and long meat, the effect of external treatment of traditional Chinese medicine on promoting wound healing was better than that of general western medicine, such as Vaseline oil yarn, Kangfuxin Liquid, 0.1% rivanol yarn, etc.; however, the regret of this paper is that most of the studies included did not report the recurrence rate, quality of life and adverse reactions, so it is impossible to further analyze these indicators. Conclusion This study shows that, compared with the western medicine external treatment which generally promotes wound healing, the traditional Chinese medicine external treatment under the theory of simmer pus and long meat has better curative effect in promoting wound healing; however, due to the small number and low quality of the included literature, it is necessary to design a rigorous and reasonable large sample randomized controlled trial for further study in the future.

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