基于文献数据挖掘中药复方治疗支气管扩张伴感染的用药规律*
作者:
作者单位:

(1. 浙江中医药大学第二临床医学院,浙江 杭州 310053;2. 浙江中医药大学附属第二医院,浙江 杭州 310005)

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R289.1;R259

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收稿日期: 2019 -12- 09
* 基金项目: 浙江省中医药科技计划项目(2017ZKL013)
第一作者简介: 戴冠冕(1995-),男,在读硕士研究生,研究方向:中西医结合呼吸系统疾病方向。
△通信作者: 蔡宛如,E-mail:caiwanru@aliyun.com


Based on Literature Data Mining, the Rule of Drug Administration of Chinese Traditional Medicine Compound for Oral Bronchodilation and Infection
Author:
Affiliation:

(1. The Second Clinical Medical College of Zhejiang University of Traditional Chinese Medicine, Hangzhou 310053, China;2. The Second Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine, Hangzhou 310005 , China)

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    摘要:

    目的基于文献数据挖掘的方式,收集近20年文献中治疗支气管扩张伴感染的中药复方,探讨支气管扩张伴感染的中医用药规律。方法 将收集所得83个处方,运用频数分析、聚类分析、关联规则进行数据挖掘,探讨其潜在的用药规律。结果 频数分析显示共涉及药物140味,使用频次≥10次的中药有29味;聚类分析反映了清肺祛痰消痈、祛瘀止血、益气养阴的治疗方法;关联规则体现清热补虚为本病的基本方法,重视消痈排脓。结论 支气管扩张的基本病机为本虚标实,在清热祛痰排脓的同时,要兼顾益气养阴、活血化瘀。

    Abstract:

    Objective Based on the method of literature data mining, collect Chinese medicine prescriptions for bronchodilation and infection in the literature in the past 20 years, and explore the rules of traditional Chinese medicine for bronchodilation and infection. Methods Eighty-three prescriptions will be collected, and data analysis will be conducted using frequency analysis, cluster analysis, and association rules to explore their potential medication laws. Results Frequency analysis showed that 140 flavors of drugs were involved, and 29 flavors of Chinese medicines were used more than 10 times. The cluster analysis analysis reflected the treatment methods of clearing the lungs and removing phlegm, removing blood stasis and bleeding, and benefiting qi and nourishing yin. Tonic deficiency is the basic method of the disease, and it is important to eliminate pus. Conclusion The basic pathogenesis of bronchiectasis is based on virtual reality. While clearing heat and expelling phlegm and purging, it is necessary to take into account the benefits of nourishing qi, nourishing yin, promoting blood circulation and removing blood stasis.

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