Objective Professor Shan believes that spleen deficiency is the underlying pathogenesis of diarrhea-type irritable bowel syndrome. The common manifestations are liver depression with spleen deficiency, yang-deficiency of spleen and kidney, and spleen-stomach damp-heat syndrome. Professor Shan’s ointment prescription for this disease is clear and well-organized. The ointment contains four parts: the main prescription, the auxiliary prescription, the adjuvant prescription, the making prescription, which are coordinated and comprehensive. the main prescription lies the core of prescription, aiming to invigorate the spleen and eliminate the dampness. the auxiliary prescription is based on the four diagnosis methods. the adjuvant prescription concentrates on the complications. The making prescription replenishes the relative deficiency of yin and yang. The ointment can enhance the body resistance and eliminate pathogenic factors with lasting drug effect, showing significant advantages to the described disease.