Objective To observe the clinical efficacy of Shenqi Jianpi Decoction in the treatment of Pediatric Anorexia of the Post-infection Spleen Deficiency Syndrome. Methods Two groups consisting 60 cases of Pediatric Anorexia of the Post-infection Spleen Deficiency Syndrome were treated with Shenqi Jianpi Decoction and BIFICO respectively for 2 weeks. Appetite, food intake and Electrogastrography(EGG) of both groups were monitored pre- and post-treatment to assess treatment efficacy. Results The treatment group recorded acure rate of 78.33% and 91.67% effectiveness; the control group recorded a cure rate of 55.00% and 76.67% effectiveness. Clinical efficacy is significantlygreater in the treatment group compared to the control group(P>0.05). The reduction in appetite and food intake in both groups post-treatment is statistically significant(P>0.05), with the treatment group recording significantlygreater reduction compared to the control group(P>0.05). Increases in dominant frequency, average amplitude and waveform response area of EGG for both groups post-treatment is statistically significant(P>0.05), with the treatment group showing significant greater increase in all parameters (P>0.05). Conclusion Shenqi Jianpi Decoction showed significant clinical efficacy in improving gastric mobility, appetite and food intake of patients with Pediatric Anorexia of the Post-infection Spleen Deficiency Syndrome.