Objective To investigate the clinical efficacy of oral Chinese medicine, internal and external treatment and Western medicine in improving thin endometrium hypomenorrhea of kidney deficiency and blood stasis syndrome. Methods 120 patients with thin endometrium hypomenorrhea of kidney deficiency and blood stasis syndrome were randomly divided into 3 groups. The control group was given bujiale + progesterone soft capsule orally(n=40); the treatment group 1 (n=40) was given the modified Bushen Huoxue Decoction, and the treatment group 2(n=40) was treated by oral administration of Zhanglao Bushen Huoxue Decoction plus moxibustion instrument(n=40). After 3 months of regular treatment, the clinical symptoms, color and quality, blood loss score, estradiol(E2) level and endometrial thickness of the three groups before and after treatment were observed. Results The total effective rates of treatment group 2 and control group were 85.0% and 90.0% respectively, which were significantly higher than that of treatment group 1(77.5%) (P<0.05); the effect of improving the total symptoms of treatment group 2 was better than that of treatment group 1; the improvement of main curative effect, intimal thickness and menstrual volume of treatment group 2 and control group were higher than or greater than that of treatment group 1; the effect of improving menstrual quality of treatment group 1 and treatment group 2 was better than that of control group; the effect of female stimulation in control group after treatment was better than that of control group The average level of estrogen was higher than that of treatment group 1 and treatment group 2; the symptom scores of three groups before and after treatment were significantly higher than those after treatment(P< 0.05). Conclusion The curative effect of Bushen Huoxue Decoction, Bushen Huoxue Decoction Combined with sitting moxibustion instrument and Western medicine is exact. There is no significant difference between the total curative effect of Bushen Huoxue Decoction Combined with sitting moxibustion instrument and hormone treatment on the disease, while the internal and external treatment has certain advantages in improving the quality and quantity of meridians.