Objective To understand the prevalence and epidemic characteristics of perimenopausal syndrome among aged women 40-60 in Xintai area,and to analyze the related influencing factors． Methods A total of 1 444 perimenopausal women aged 40 to 60 of Xingtai people’s hospital from January to December 2019 in Xintai City were surveyed, modified Kupperman scale and a self-designed general information questionnaire, physical examinations and laboratory examinations were investigated. Results There were 832 patients with perimenopausal syndrome in 1 444 perimenopausal women(57.6%). Among the perimenopausal syndrome patients， the mild， moderate and severe perimenopausal syndrome patients was 37.6%(543), 18.4%(266) and 1.6%(23). Common symptoms included fatigue 746(51.7%), mood swings 722(50.0%), insomnia 697(48.3%). The prevalence of fatty liver disease was 26.6%, hypertension 7.4%, hyperlipidemia 2.8% and high blood sugar 2.3%. In terms of severity grading characteristics of perimenopausal syndrome, there were statistically significant differences in cholesterol, triglycerides, LDL cholesterol, uric acid (P<0.05).Multivariate analysis showed that the risk factors were nature of work, sleep patterns, menstrual status. Conclusion The prevalence of perimenopausal syndrome in women aged 40-60 years is high in this area, most of them are mild to moderate symptoms, strengthen the health education of perimenopausal period, improve women’s health knowledge, and then improve the quality of life.