Objective To evaluate the efficacy and safety of acupuncture-related therapies for psoriasis through a network Meta-analysis. Methods A total of seven electronic databases including CBM, CNKI, Wanfang, VIP, PubMed, Embase, and the Cochrane Library were searched for psoriasis, from inception to October 2020. The included literature were screened, extracted, and assessed for bias.Documents were analyzed by Stata 15.0 in network Meta-analysis. Results A total of 27 studies(n=2 612) were included, which involved 12 kinds of acupuncture and moxibustion therapies: acupuncture+western medicine, acupuncture+bloodletting+western medicine, fire needle+western medicine, moxibustion+western medicine, bloodletting+western medicine, acupuncture+fire needle+bloodletting, acupuncture+fire needle, acupuncture, bloodletting, fire needle+bloodletting, acupuncture+bloodletting and fire needle. In the network meta-analysis, 26 RCTs with total effective rate as the outcome index involved 11 kinds of acupuncture therapy, and 18 RCTs with PASI as the outcome index involved 10 kinds of acupuncture therapy. Sorting results of surfaces under the cumulative ranking curves regarding effective rates: acupuncture+bloodletting+western medicine>acupuncture+bloodletting>acupuncture+fire needle>acupuncture +fire needle+bloodletting>bloodletting>acupuncture+western medicine>bloodletting+western medicine>fire needle+bloodletting>fire needle+western medicine>acupuncture>fire needle>western medicine.Sorting results of surfaces under the cumulative ranking curves regarding the change of PASI: moxibustion+western medicine>acupuncture+western medicine>acupuncture+fire needle+bloodletting>bloodletting+western medicine>fire needle+western medicine>acupuncture+fire needle>fire needle+bloodletting>acupuncture>bloodletting>fire needle>western medicine. Network Meta-analysis shows that the ten therapies were better than western medicine, including acupuncture+bloodletting+western medicine, acupuncture+bloodletting, acupuncture+fire needle, acupuncture+fire needle+bloodletting, bloodletting, acupuncture+western medicine, bloodletting+western medicine, fire needle+bloodletting, fire needle+western medicine and acupuncture in the treatment of psoriasis was better than that of conventional western medicine.While for the improvement of PASI, four therapies include moxibustion+western medicine, acupuncture+western medicine, fire needle+western medicine, fire needle+bloodletting were better than conventional western medicine. Conclusion Bloodletting is recommended for monotherapy; acupuncture combined with bloodletting, and western medicine are recommended for combined therapy. However, clinical treatment needs to be cautiously administered due to the few and poor quality studies.