Inflammation is a major factor in a variety of chronic diseases and their progression， including inflammatory bowel diseases， autoimmune diseases， cardiovascular disease， neurodegenerative diseases， and even cancer. Cnidium ninidium and its preparations are widely used in the clinical treatment of gynecological inflammation， atopic dermatitis， eczema， arthritis and other diseases. Osthole is the main coumarins chemical component in Cnidium of the genus Umbelliferae， which has anti-inflammatory and analgesic， antibacterial and antipruritic， antioxidant and neuroprotective effects. According to research status， this review summarized our current understanding of the pharmacological effects of that covers literature in the recent 10 years， aiming to provide theoretical basis for clinical application research.