Objective To investigate the main acupoint intervention methods for restless legs syndrome(RLS) in recent years and analyze the regularity of acupoint prescriptions of corresponding intervention methods. Methods Using bibliometrics methods, we searched the CNKI, Weipu and Wanfang databases for the clinical literature of stimulating acupoint treatment for RLS in the past 40 years, and statistically analyzed the acupoint intervention methods and the rules of acupoint selection. Results The acupoint intervention method for RLS was mainly acupuncture(59.26%). Among the common acupuncture methods, Zusanli, Sanyinjiao, Yanglingquan and Chengshan are the main selection points; Zusanli and Sanyinjiao points have the highest compatibility support. The other acupoint stimulation therapy is Zusanli, Sanyinjiao, Yanglingquan and Chengshan as the main points; Zusanli and Yanglingquan acupoints have the highest compatibility support. Conclusion Compared with other acupoint stimulation therapies, ordinary acupuncture methods are relatively mature and reliable in the treatment of RLS. The point selection of common acupuncture methods and other acupuncture point stimulation therapy is mainly concentrated in the lower limbs. The acupoint selection group has regular rules, and the different intervention methods are roughly the same.