Objective To analyse the characteristics of TCM syndrome in patients with refractory gout and its epidemiology, medical conditions, medications and other clinical features. Methods From January 2016 to June 2021, a retrospective analysis was conducted on refractory gout patients hospitalized in the Rheumatology Department of Yunnan Provincial Hospital of Traditional Chinese Medicine, and the sex, age, precipitating causes, course and comorbidity distribution of patients were counted, and the previous and in-hospital medications of different patients were recorded, and the most commonly used drug combinations in the hospital were analyzed. Results A total of 730 patients were enrolled in this study, including 696 males and 34 females, and the age groups were mainly concentrated between 40 and 80 years old, and the symptoms were mainly damp and heat, spleen deficiency and dampness resistance, and cold and wet paralysis. In the acute stage, it is mostly seen that the damp heat contains the evidence and the cold and wet paralysis obstruction, the remission period is mainly the spleen deficiency and wet obstruction, and the chronic stage is mainly the sputum stasis obstruction and liver and kidney deficiency; often combined with hypertension, fatty liver, osteoarthritis and other diseases, the treatment is mainly based on the combination of traditional Chinese and Western medicine, the early use of anti-inflammatory and analgesic drugs, and the later stage is mainly based on uric acid-lowering drugs. Conclusion Refractory gout patients are mainly male, with the characteristics of age, long course and other characteristics, and are easy to combine other diseases, especially hypertension, fatty liver, osteoarthritis, “sputum stasis” is the key pathogenesis.