Objective To explore the correlation of TCM syndrome with clinical stage and laboratory examination in patients with gout. Methods A total of 2 092 gout patients hospitalized in the Department of Rheumatology, Yunnan Provincial Hospital of Traditional Chinese Medicine from January 2016 to June 2021 were selected. The clinical data, TCM syndromes and laboratory examinations of the patients were collected. Results During the investigation, dampness-heat accumulation syndrome, cold-dampness obstruction syndrome, spleen deficiency dampness obstruction syndrome, phlegm-stasis obstruction syndrome and liver and kidney deficiency syndrome are the main syndromes. We found that the age of patients, onset age, clinical stage, and interleukin-1β(IL-1β), Fibrinogen(FIB) and D-dimer in laboratory examination were associated with TCM syndrome type. Conclusion Age, onset age, clinical stage, IL-1β, FIB and D-dimer may be the factors causing the difference of TCM syndromes in patients.