Objective To study the effect of warming needle moxibustion combined with fumigating and washing with traditional Chinese medicine on patients with rheumatoid arthritis(RA). Methods A total of 150 patients with RA admitted to the hospital from October 2020 to October 2021 were divided into observation group(75 cases) and control group (75 cases) by random number table method. The control group underwent warming needle moxibustion, and the observation group underwent warming needle moxibustion combined with fumigating and washing with self-made traditional Chinese medicine. The two group were compared in terms of clinical effect, improvement of clinical symptoms, changes in laboratory indicators, and immune function after 1 month of treatment. Adverse reactions were observed. Results The total treatment response rate in the observation group(96.00%) was significantly higher than that in the control group(85.33%) (P<0.05). The clinical symptom scores of observation group were significantly lower than those of the control group (P<0.05). The levels of interleukin-1(IL-1), C-reactive protein(CRP), erythrocyte sedimentation rate(ESR) and rheumatoid factor(RF) in the observation group were significantly lower than those in the control group (P<0.05). The levels of CD3+, CD4+ and CD4+/CD8+ were significantly higher, and the level of CD8+ was significantly lower in the observation group than in the control group (P<0.05). The incidence of adverse reactions showed no significant difference between the two groups (P>0.05). Conclusion Warming needle moxibustion combined with fumigating and washing with self-made traditional Chinese medicine can effectively improve the clinical effect in patients with RA, and relieve related clinical symptoms and local inflammatory response.