Objective To investigate the postoperative rehabilitation effect of SuperPATH minimally invasive hip replacement combined with acupuncture and moxibustion for femoral neck fracture. Methods A total of 49 patients were actually enrolled, and the SuperPATH approach was used for minimally invasive hip arthroplasty in both groups. The operation was completed by the same group of physicians and combined lumbar and epidural anesthesia was used. Both groups received rehabilitation exercise; The control group received routine anti-inflammatory, anticoagulant and analgesic treatment. Acupuncture group plus acupuncture giant thorn movement method on the basis of control group. Results In fact, 49 cases were included, and there were no significant differences in age, BMI, gender, overall mean and distribution of affected areas and underlying diseases between the two groups(P>0.05). There was no significant difference in the overall mean and distribution of Harris score and VAS score between the two groups before treatment(P>0.05). There were significant differences in Harris score and VAS score between the two groups before and after treatment(P<0.05). There were statistically significant differences in the overall mean of Harris assessment between the two groups(P<0.05), and there were statistically significant differences between the two groups(P<0.05). There was statistical difference in the overall distribution of VAS score at 7 days of treatment between 2 groups(P<0.05), and the difference at 7 days of treatment was statistically significant(P<0.05). There was no statistically significant difference in the overall distribution of VAS score between 2 groups at 30 days after treatment(P>0.05), and no statistically significant difference in the difference at 30 days after return visit(P>0.05).The difference of ESR between 2 groups at 7 days after treatment was statistically significant(P<0.05). There was statistical difference in the overall distribution of C-RP in acupuncture group before and after treatment (P<0.05). Conclution The results of this study indicate that SuperPATH minimally invasive hip replacement combined with acupuncture and acupuncture for the treatment of femoral neck fracture can improve hip function, relieve pain, reduce postoperative complications, reduce erythrocyte sedimentation rate and C-reactive protein level, and may reduce inflammatory response, thus speeding up postoperative recovery.