Objective Through knowledge mapping visualization software, the research status, hot spots and results of traditional Chinese medicine (TCM) treatment of chemotherapy induced nausea and vomiting (CINV) in the past 20 years were explored, providing reference for further research in this field. Methods With "traditional Chinese medicine", "chemotherapy and vomiting" as the theme words. The period is from January 1, 2002 to December 31, 2021. The relevant literature included in the Chinese National Knowledge Infrastructure(CNKI) , Wanfang Data, China Science and Technology Journal Database and SinoMed was searched. Useing the CiteSpace.6.1.R1 software conducted the metrological analysis of the literature, and drew, analyzed the relevant knowledge map. Results In total, 1 116 analytical literature articles were included. From 2002 to 2021, the number of documents on CINV in China was on the rise, with the fastest growth between 2014 and 2021(the annual average number of articles published was 82.38). The total number of core authors?蒺 publications was 567, accounting for 50.8% of all publications (>50%). A total of five closely cooperative author institutions were formed. High frequency keywords of traditional Chinese medicine in the treatment of CINV are chemotherapy induced vomiting, tumour, breast tumour, acupoint application, and acupoint injection. The clustering map shows that all the keywords are clustered into 12 categories. A total of 16 keywords participated in the outburst, among which the research hotspots in the past two years included lung cancer, adverse reaction and acupoint application, and soon. Conclusion The combination of TCM and antiemetic drugs, the application of external treatment of TCM such as acupoint application and ear acupoint pressing, and the symptomatic treatment of tumors are the research hotspots of TCM in the treatment of CINV. Diversified treatment programs of integrated Chinese and western medicine and traditional Chinese medicine characteristics are the development trend of future research.