Objective To observe the main clinical symptoms，sphenopalatine ganglion penetration through sphenopa-latine acupoint awn acupuncture under CT guidance in the treatment of allergic rhinitis. Methods A total of 72 patients with allergic rhinitis were randomly divided into experimental and control groups. In experimental group, sphenopalatine ganglion was pierced by CT guided sphenopalatine awn acupuncture. The control group was treated with acupuncture sphenopalatine point combined with conventional acupuncture. Results The total effective rate was 94.44% in the experime-ntal group and 77.78% in the control group. The difference between the two groups was statistically significant. The index improvement of experimental group was better than that of the control group. Conclusion In the treatment of allergic rhinitis, puncture of sphenopalatine ganglion with awn needle under CT guidance is a unique treatment method, which increases the accuracy and safety of puncture of sphenopalatine ganglion, and provides a certain reference for puncture angle and depth without CT guidance.