The ancient Chinese astronomical theory holds that "heaven and man correspond", and the physiological and pathological changes of man are closely related to those of nature. The author summarized the influence of ancient astronomical theories on the occurrence and development of meridians and acupoints, and found that the theories of divination and astrology in ancient astronomy were closely related to the theoretical system of the human body operating Qi and blood, preventing and treating diseases constructed by the meridians and acupoints. The ancient astronomical theory guided the construction of meridian system and explained meridian circulation. It also affects the naming of acupoints, the number of acupoints and clinical treatment ideas.