老年性骨质疏松症伴股骨粗隆间骨折患者中医证型证素及舌象规律研究
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(1. 天长市中医院,安徽 天长 239300;2. 黑龙江中医药大学,黑龙江 哈尔滨 150040;3. 云南中医药大学,云南 昆明 650500)

作者简介:

程永胜(1980-),男,主治医师,研究方向:中医骨科。

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基金项目: 云南省教育厅科学研究基金研究生项目(2021Y486);云南中医药大学大学生创新创业训练计划项目(X2021018)


Studying Characteristics of TCM Syndrome Elements and Image Tongue in Patients of Senile Osteoporosis with Femoral Intertrochanteric Fracture
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(1. Tianchang Hospital of Traditional Chinese Medicine, Tianchang 239300, China; 2. Heilongjiang University of Chinese Medicine, Harbin 150040, China; 3. Yunnan University of Chinese Medicine, Kunming 650500, China)

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    摘要:

    目的 研究老年性骨质疏松症伴股骨粗隆间骨折患者的中医证型证素以及中医舌象特征。方法 选取天长市中医院的154例老年性骨质疏松症伴股骨粗隆间骨折住院患者,采集中医证型证素以及基线资料,包括年龄、性别等。通过Excel统计分析患者舌象以及证型证素分布情况,采用SPSS 20.0和SPSS Modeler 18.0软件进行聚类分析和关联性分析。结果 纳入的154例患者中,男性57例(37.01%),女性97例(62.99%),中医证型分布频次从高至低依次为肾阳亏虚证(33.12%)、肝肾不足证(27.92%)、脾阳亏虚证(19.48%)、脾肾阳虚证(14.29%)、气滞痰阻证(2.60%)和痰瘀互结证(2.60%);中医证素总计出现373频次,病位证素主要包括肾(116/31.10%)、脾(52/13.94%)、肝(43/11.53%);病性证素包括阳虚(103/27.61%)、阴虚(43/11.53%)、气滞(4/1.07%)、痰(8/2.14%)、瘀(4/1.07%)。频数≥50次的舌象因素10个,软萎舌、白苔、舌下络脉淡紫、舌苔润、舌质淡红、嫩舌、舌苔干燥、舌下络脉紫黑、剥落苔、少苔;累计出现756频次,贡献百分比为70.13%。关联规则分析支持度前三的是:舌苔润与点刺舌and腻苔;舌苔润与点刺舌and淡白舌;舌苔润与点刺舌and淡白舌and腻苔。舌象研究结果提示,虚、瘀和痰是病理因素。聚类分析舌象分为9类。C1:软萎舌、舌下脉络淡紫、淡红舌、舌苔干燥;C2:暗舌、白苔;C3:瘦小舌、红舌、无苔;C4:嫩舌、舌下脉络曲张、灰黑苔;C5:胖大舌、裂纹舌、舌苔滑;C6:黄苔、舌下脉络紫黑、绛舌;C7:淡白舌、少苔、齿痕舌;C8:腻苔、厚苔;C9:点刺舌、舌苔润。与关联规则分析结果一致。结论 老年性骨质疏松症伴股骨粗隆间骨折住院患者的病位证素包括肾、脾和肝;病性证素包括阳虚、阴亏、气滞、痰、瘀。患者舌象具有一定的规律;舌苔润与点刺舌、淡白舌、腻苔是常见组合舌象;舌象研究结果提示,气(阳)虚、痰湿血瘀是主要病机。

    Abstract:

    Objective To study the characteristics of TCM syndrome elements and tongue image in senile osteoporosis with intertrochanteric fracture. Methods 154 inpatients in our hospital were selected to collect the TCM syndrome types and syndromes and baseline data, including age, gender, etc. Microsoft Excel was used to analyze the tongue image of patients and the distribution of syndrome types and symptoms. SPSS20.0 and SPSS Modeler 18.0 were used for cluster analysis and correlation analysis. Results Among 154 patients with senile osteoporosis and intertrochanteric fracture, there were 57 males (37.01%) and 97 females (62.99%). The frequency distribution of TCM syndrome types from high to low were kidney Yang deficiency syndrome(33.12%), liver and kidney deficiency syndrome(27.92%), spleen Yang deficiency syndrome (19.48%), spleen and kidney Yang deficiency syndrome (14.29%), Qi stagnation and phlegm obstruction syndrome (2.60%) and phlegm and blood stasis syndrome(2.60%). There were 373 frequency of TCM location of syndrome elements, including kidney (116/31.10%), spleen (52/13.94%) and liver (43/11.53%). The pathogenic syndromic elements included Yang deficiency (103/27.61%), Yin deficiency (43/11.53%), Qi stagnation (4/1.07%), phlegm (8/2.14%) and blood stasis (4/1.07%). Ten factors of tongue image that frequency ≧50 times: soft withered tongue, white moss, hypoglossal veins mauve, moist tongue, reddish tongue, tender tongue, dry tongue, hypoglossal veins mauve black, peeling moss, less moss; The cumulative occurrence of 756 frequency, the contribution percentage is 70.13%. The top three supporting degrees of association rules analysis are: moistening tongue, prickling tongue and greasy coating. Tongue coating moistened and punctured tongue and pale tongue; The tongue is moist and prickly and the tongue is pale and greasy. It is suggested that deficiency, blood stasis and phlegm are pathological factors. Cluster analysis of 9 categories, C1: soft withered tongue, hypoglossal vein lavender, light red tongue, tongue coating dry; C2: dark tongue, white moss; C3: thin uvula, red tongue, no moss; C4: tender tongue, varicose sublingual veins, gray and black moss; C5: fat tongue, cracked tongue, tongue coating slippery; C6: yellow moss, sublingual vein purple black, Jiang tongue; C7: pale white tongue, little moss, teeth marks tongue; C8: greasy moss, thick moss; C9: Point thorns tongue, tongue coating embellish. It is consistent with the analysis results of association rules. Conclusion The TCM location of syndrome elements of senile osteoporosis with intertrochanteric fracture include kidney, spleen and liver. The pathogenic syndromic elements include Yang deficiency, Yin deficiency, Qi stagnation, phlegm and blood stasis. The patient‘s tongue image has a certain law; Tongue embellish and punctate tongue, pale white tongue, greasy moss is a common combination of tongue; The results of tongue image study suggested that Qi(Yang) deficiency, phlegm dampness and blood stasis were the main pathogenesis.

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  • 收稿日期:2022-09-20
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  • 在线发布日期: 2023-04-25
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