With many years of clinical experience, professor Peng Jiangyun believes that "deficiency of spleen and kidney, phlegm dampness and blood stasis" is the key to the pathogenesis of gouty nephropathy, and treatment should be based on "regulating the spleen and kidney together, reforming from the bottom of the disease" and "resolving dampness and turbidity, taking into account both the symptoms and the root cause". It is also advocated that the diagnosis and treatment of gouty nephropathy should be combined with Chinese and Western medicine, with the "treatment variation based on disease diagnosing" as the first priority, and the "treatment variation based on syndrome differentiation" combined with the "treatment variation based on symptom differentiation", with excellent clinical results. This paper summarizes the experience of professor Peng on gouty nephropathy and her experience in distinguishing and treating gouty nephropathy.