Objective To explore the acupoint selection rules of auricular therapy for simple myopia using association rules and cluster analysis, and to analyze appropriate stimulation methods through statistical analysis. Methods We searched seven databases, including CNKI, SinoMed, WanFang, VIP, PubMed, Cochrane library, and Embase from the inception of the database to September 15, 2021, to retrieve clinical trial research literature on auricular acupuncture for simple myopia. We used Microsoft Excel 2019 to establish the database, and Review Manager 5.4 to evaluate the risk of bias of the included literature. We used IBM SPSS Statistics 21 and R 4.2.1 for auricular point set visualization analysis, auricular point network analysis, and cluster analysis. Results A total of 57 groups of auricular points prescription were included in this study, including 23 auricular points. Among them, the auricular points with higher cumulative application frequency were LO3 54 times (15.00%), CO12 49 times (13.61%), TG21 49 times (13.61%), AT11 47 times (13.06%), CO10 44 times(12.22%); the common auricular point combination is TG21 and AT11; the stimulation method used mostly is cowherb seed (78.95%); These Auricular acupuncture can form four groups: TG21-AT11-LO3-CO12-CO10-CO13-CO15, TF4, AT4 and AT3.4i. Conclusion Auricular point therapy for simple myopia is guided by TCM theory and involves the selection of acupoints based on LO3, TG21, and AT11, as well as the individual patient‘s condition. Through the analysis of a large dataset, this study explored the feasibility of acupoint selection and compatibility rules for auricular therapy in treating simple myopia, offering valuable insights for clinical research and experimental design.