Oligoasthenospermia has more than half of the causes that cannot be identified, and circadian rhythm disturbances may be one of the major causes. Based on the theory of traditional Chinese medicine(TCM). This paper discusses the pathogenesis and treatment characteristics of idiopathic oligoasthenozoospermia with circadian rhythm disorder. It is considered that its basic pathogenesis lies in the functional dereliction of duty of "kidney dominates reproduction" and the loss of Yin and Yang in regulation, Namely, Yang does not enter Yin and the initial Yang cannot grow. In the pathogenesis of semen, it is manifested as "essence and cold". Thus, the paper proposes "revitalizae Xiongyang method", which is intended to regulate the Yin and Yang of the kidney, assist Yang growing, and revitalize male reproductive function. As a classic representative formula for revitalizing Xiongyang, Tianxiong San has the functions of warming and evoking kidney-Yang, down-regulating Yin and up-regualting Yang, and assisting Yang growing, which meets the treatment requirements of idiopathic oligoasthenospermia with circadian rhythm disorder. Combined with modern research progress and prescription analysis, this prescription may have a certain therapeutic effect in regulating circadian rhythm and improving oligoasthenospermia. Therefore, it is proposed that Tianxiong San can be used in the treatment of idiopathic oligoas-thenospermia with circadian rhythm disorder in order to provide new ideas for the clinical treatment of TCM.