Male climacteric syndrome occurs in the transition stage of middle and old age. Due to the decline in physical function caused by old age, the quality of life of men in the later stage of life may be reduced to varying degrees, thus affecting normal work and life. There is a correlation between MCS and decreased skeletal muscle mass. However, the current research on the correlation is somewhat insufficient. To explore the correlation between male climacteric syndrome and skeletal muscle mass will provide some ideas for the future study of MCS.