As a classification of sexual dysfunction, male hyposexuality is closely related to consciousness and is a common andrology disease in clinic. "Qi is the ancestor of Shen" emphasizes the nourishing and regulating function of Qi on Shen. Starting from the relationship between Qi and Shen, this paper discusses the physiological and pathological relationship between male hyposexuality and personal Qi. Physiologically, the generation and arousal of sexual desire depend on the nourishment and regulation of Qi. Pathologically, the weakness of Qi leads to the lack of motivation and material basis for the generation and arousal of sexual desire. Therefore, the treatment of this disease should be based on the principle of invigorating Qi, and the treatment methods of invigorating heart Qi, benefiting stomach Qi and warming kidney Qi can be used to make the Shen rely on the deficiency of invigorating Qi. Based on the theory of "Qi is the ancestor of Shen", this paper discusses the pathogenesis and treatment rules of male hyposexuality in order to provide ideas for clinical treatment of male hyposexuality.