Abstract:Aim to study the chemical constituents of ethyl acetate extraction of Aralia chinensis Linn. var. nuda Nakai. Method The ethyl acetate part of 70% ethanol extract of Aralia chinensis Linn. var. nuda Nakai was purified by silica gel, ODS, Sephadex LH-20 and semi-preparative HPLC, and the structure of the compound was identified by the physicochemical properties and spectral data. Results Twelve compounds were isolated and identified as phthalic acid, bis-(2, 5-dimethylhexyl) ester (1), (9E)-8,11,12-trihydroxyoctadecenoic acid methyl ester (2), methyl (9S,10R,11E,13R)-9,10,13-trihydroxyoctadec-11-enoate (3), capillasterolide (4), hexacosane (5), (-)-loliolide (6), methyl hematinate (7), tyraminel (8), (S)-Methyl 2-acetamido-3-phenylpropanoate (9), 3-hydroxy-4-methoxybenzoic acid (10), vanillic acid (11), p-hydroxybenzoic acid (12). Conclusion Compounds 1-10 are isolated from this genus Aralia for the first time, and compounds 1-11 were first isolated from the plant.