The "Huangdi Neijing" contains a rich and detailed explanation of the mechanism of disease regression, in which the exposition of the signs and mechanisms of disease healing occupies an important position. This article, through the study of the "Huangdi Neijing," It is pointed out that the "Huangdi Neijing" discusses various signs of healing; it adopts color vision, pulse diagnosis, and the use of the law of the five elements to elaborate the mechanism of healing; among them, the positive recovery of the evil is the most basic core of healing; in addition, there are still Yin and Yang in order to pass, Ying and Wei are harmonized, the reverse of the gas can be returned, Qi restoration, and the standard and the original get to the healing mechanism; it also explores the law of healing of the time of Tianren Correspondence and other contents. A comprehensive and in-depth study of the theory of the "Huangdi Neijing" on the signs and mechanisms of healing is of great value and significance in strengthening the study of classical theories and improving the level of clinical diagnosis.