Objective This study aimed to evaluate the clinical efficacy of Baijiang Tongyu Decoction in treating chronic prostatitis/chronic pelvic pain syndrome with a damp-heat and blood stasis pattern. Methods A total of 60 male outpatients were included in this clinical trial. The treatment group received oral administration of Baijiang Tongyu Decoction, while the control group was administered Longqing Capsules. Results The findings indicated that the treatment group exhibited a higher overall effectiveness compared to the control group. After treatment, no significant differences were observed between the two groups in terms of pain, quality of life, urination status, and the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) scores. However, significant differences (P<0.05)were noted in the changes in white blood cell counts and lecithin body levels between the two groups. Conclusion Baijiang Tongyu Decoction demon-strated superior clinical outcomes in terms of overall treatment effectiveness, improvement in white blood cell counts, and enhancement of lecithin body levels compared to Longqing Capsules. This suggests potential clinical utility and broader application significance.