Based on the theory of dialectical treatment of traditional Chinese medicine, professor Wang Zulong proposed the theoretical approach to governance of "three-level diagnostic approach" of disease differentiation, dialectic, and main symptom discrimination. Due to the common occurrence of andrological diseases, professor Wang put forward the academic thought of "distinguishing the primary disease" in view of the andrology comorbidities, and analyzed the common andrology comorbidities such as ED/PE comorbidities, DM/ED comorbidities, CP/ED comorbidities, and CP/BPH comorbidities, which provided a new diagnosis and treatment idea for andrology diagnosis and treatment.