Henoch-Sch?觟nlein purpura(HSP) is a common IgA-mediated hypersensitivity vasculitis, categorized under the traditional Chinese medicine(TCM) concepts of "purpura" and "blood syndrome" with multisystem involvement. Professor Xi Jianyuan, based on Liu Wansu‘s "Xuanfu Qi-Fluid Theory" and his own clinical experience, proposes that the core pathogenesis of HSP lies in "obstructed Xuanfu(microscopic functional pores), dysregulated Qi movement, and malnourished viscera". By leveraging the ascending and dispersing properties of wind-dispelling herbs to "open the Xuanfu and expel pathogens", he aims to restore Qi-blood circulation and achieve therapeutic efficacy. This article systematically summarizes Professor Xi‘s application of wind-mediating herbs guided by Xuanfu theory, providing insights for the clinical treatment of HSP.