In order to master the evolution law of the Communist Party of China promoting the inheritance and innovation development of traditional Chinese medicine in Yunnan. The article the motivation of the Party leading the inheritance and innovation development of traditional Chinese medicine in Yunnan from the aspects of serving the central task of the Party and the state in the hundred years, meeting the diversified health needs of the people of Yunnan, and activating the subjectivity of Yunnan traditional Chinese medicine culture. It is believed that on the unity of party nature and people‘s nature, the unity of historical logic and real demand, and the unity of Marxism "essence" and traditional Chinese medicine "essence" constitute the evolution law of the Party promoting the inheritance and innovation development of traditional Chinese medicine in Yunnan, and provide an important reference for the high-quality of traditional Chinese medicine in Yunnan in the new era.